rifampin will reduce the level or result of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unknown.tecovirimat will increase the level or impact of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Use Warning/Check. Tecovirimat can be a weak inhibitor of CYP2C8 and CYP2C19. Watch for adverse conseque

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